Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer

The Role of Transurethral Resection in Trimodal Therapy for Muscle-Invasive Bladder Cancer

While radical cystectomy (RC) with pelvic lymph node dissection (PLND) represents the accepted gold standard for the treatment of muscle-invasive bladder cancer, this treatment approach is associated with significant morbidity. As such, bladder preservation strategies are often utilized in patients who are either deemed medically unfit due to significant comorbidities or whom decline management...

novel optical technology in bladder cancer diagnosis and treatment

Theranostic Agents for Photodynamic Therapy of Prostate Cancer by Targeting Prostate-Specific Membrane Antigen.

Prostatectomy has been the mainstay treatment for men with localized prostate cancer. Surgery, however, often can result in major side effects, which are caused from damage and removal of nerves and muscles surrounding the prostate. A technology that can help surgeons more precisely identify and remove prostate cancer resulting in a more complete prostatectomy is needed. Prostate-specific membr...

Our experience with photodynamic diagnosis and photodynamic therapy for lung cancer.

The diagnosis of lung cancer was significantly enhanced by the development of the fiberoptic bronchoscope in 1965. Since then, advances in photosensitizers and light sources have brought photodynamic medicine into the light. This article offers an historic overview of the emergence of photodynamic medicine through the perspective of a pioneer with more than 30 years' experience. Along with a di...

Ruthenium Phthalocyanines NOVEL WATER SOLUBLE AGENTS FOR PHOTODYNAMIC CANCER THERAPY

Photodynamic therapy is a clinical technique employing the combination of light, oxygen and a sensitising compound to induce the photochemical destruction of unwanted tissue. Light therapy has been known for some time, but it was not until the earlierpart of this century that the first clinical work was performed using sensitisers and light. More recently a sensitising compound of a complex mix...